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The application of diferrocenylimine ligands for asymmetric transfer hydrogenation of ketones

Zhang Yu-Mei, LIU Peng, Qiu Hong

Two Novel planar chiral diferrocenylimine (3a) and (3b) were prepared for the Iridium catalyzed asymmetric transfer hydrogenation of aromatic ketones. The results show that the activity and enantioselectivity of the chiral iridium catalyst are very sensitive to the substrate structure. Ir(I)-catalyzed asymmetric transfer hydrogenation of acetophenone resulted in moderate to good yield and lower enantioselectivity; asymmetric transfer hydrogenation of proopiophenone and 2- benzoylpridine resulted in lower yield and lower enantioselectivity; as for 4-benzoylpridine, Good results have been achieved.