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Teaching Sharpless Epoxidation-A New Approach

Saroj Agrawal, Virendra Pal and P. S. Kalsi

Sharpless enantioselective epoxidation of achiral primary allyl alcohols is one of the best reaction discovered during the last about three decades. During teaching programmes, it is observed that generally students lack a sound basic background on which the teaching of such an advanced topic in the class is based. Moreover, in general the students often question the utility of the topic being taught, in every day life in industry/ design of drug/ biochemical aspects etc. The authors here present the example of Sharpless epoxidation, the way, it should be taught by providing: • Background knowledge • The reaction • Some applications of the reaction