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Synthesis, Characterization and Antimicrobial Evaluation of Schiff’s Base and 4-Thiazolidinone Derivatives of Vanillin

Vikram R. Dangar, Jagdish V. Dodia and Viral R. Shah

In the present investigation, it was our interest to synthesize some new derivatives containing 4-(o- Chlorobenzyloxy)-3-methoxybenzaldehyde moiety incorporated with different biologically active heterocycles such as Schiff’s base and Thiazolidinones derivatives. Schiff’s base of N-Aryl-1,-4-(o-chlorobenzyloxy)-3-methoxyphenyl-1-ylazomethines and N-Aryl-1,4-(o-chlorobenzyloxy)-3-methoxyphenyl-1-yl-4-thiazolidinones were prepared. All the prepared compounds were characterized by their spectral (I.R., N.M.R., Mass) data and screened for their antimicrobial activities.