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Simultaneous spectrophotometric estimation of amlodipine and nebivolol in tablet dosage form

BhushanM.Firake, sanjayG.Walode, sadip D.Firke

A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of amlodipine and nebivolol (in pure and in their pharmaceutical dosage form). The method involves solving of simultaneous equations based on measurement of absorbances at two wavelengths 242.0nm and 286.8nm which are the wavelength maxima of amlodipine and nebivolol, respectively. The method was successfully applied for simultaneous determination of amlodipine and nebivolol in binary mixture.