Биохимия: индийский журнал
ISSN (PRINT): 0974-7427

Абстрактный

Simultaneous Determination of Simvastatin and Ezetimibe by Liquid Chromatography

B. Neelima, P. Ravi Kumar, V. Hima Bindu and Y. Rajendra Prasad


A simple, precise and rapid RP-HPLC method was developed for the simultaneous determination of simvastatin and ezetimibe in combined pharmaceutical dosage forms. The method was carried out on a Shim-pack, RP-C18 column using a mixture of acetonitrile : 0.1% v/v orthophosphoric acid and detection was done at 239 nm using external standard method as quantitation. The linearity range of simvastatin and ezetimibe were 0.1 to 25 =g/mL. The intra-day and inter-day precision were in the range of 0.16-0.20 and 0.25-0.46 for simvastatin, 0.86-1.43 and 0.35-0.93 for ezetimibe.


Индексировано в

  • КАСС
  • Google Scholar
  • Открыть J-ворота
  • Национальная инфраструктура знаний Китая (CNKI)
  • CiteFactor
  • Космос ЕСЛИ
  • МИАР
  • Секретные лаборатории поисковых систем
  • Евро Паб
  • Университет Барселоны
  • ICMJE

Посмотреть больше

Журнал ISSN

Индекс Хирша журнала

Flyer

Журналы открытого доступа