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Screening and identification of endophytes from the seeds of Castonospermum austral producing alpha-glucosidase inhibitors

Ren Peng, Jianqiao Zhu, Yanchao Zhou, Menglu Chen, Jing Fu

Alpha-glucosidase inhibitors are potent inhibitors of HIV and HCV. Endophytes fromthe seeds of Castonospermum austral producing alphaglucosidase inhibitors with high activity were screened. The strain which produced alpha-glucosidase inhibitors with the highest inhibition rate of 23.21% was obtained. The strain was identified as Bacillus cereus according to 16S ribosomal DNA sequence,morphological, physiological and biochemical features.