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Salivary Proteomics in Early Diagnosis of Oral Cancer-A Review

Anitha R Sagarkar, Vikas Kumar, Kavitha Prasad and Roopa Rao

Oral cancer is a predominant health issue in India affecting large number of population, with tobacco as one of the main preventable etiological factor for it. Early diagnosis is essential factor in lessening the burden of disease and molecular non-invasive (Salivary-based) diagnostics is considered as the up trending approach recently. Saliva is collected from individuals either from single or multiple glands and is generally stimulated or non-stimulated type. Saliva sample is prepared and fractionated to identify the proteome sequence using any of the advanced techniques.