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Norfloxacin : A Therapeutic Review

Prabodh Chander Sharma, Ankit Saneja and Sandeep Jain

This therapeutic review illustrates the chemistry, pharmacology, pharmacokinetics, antibacterial spectrum and interactions of norfloxacin, a fluoroquinolone antibiotic. A special emphasis is laid on the clinical efficacy and antimicrobial spectrum of norfloxacin and its place in clinical therapy. Norfloxacin is generally well tolerated and its adverse effects are not very severe. Regardless of the fact that norfloxacin was introduced long back and many new fluoroquinolones have been introduced thereafter, it still holds a very important place in treatment of several infectious diseases.