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Interaction of Co (II), Ni (II), Cu (II) and Zn (II) Transition Metal Ions with Sulfamethoxazole Drug and Phenyl Alanine in 40% Alcohol Water Medium

B. K. Magare and M. B. Ubale

The interaction of Co (II), Ni (II), Cu (II) and Zn (II) transition metal ions with sulfamethoxazole drug and phenyl alanine amino acid have been studied pH metrically at 27oC temperature and 0.1 M ionic strength (NaClO4) in 40% v/v alcohol water medium. The pKa of ligands and log K of binary metal complexes were determined and correlated with basicity of ligands and atomic number, atomic radii of metal ions.