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Experimental study on synergism antibacterial action of Er Yanning in vitro

Wu Liping, Hu Xiaoqian, Li Meng, Hou Jinjie, Li Ruiyu

Objective: To observe synergistic antibacterial effect of Er yanning in vitro. Methods: The Er Yanning NO1 (the main component of rheum officinale),No2 (main component of Scutellaria baicalensis, phellodendron bark) and Er yanning NO1-NO2 compatibility antibacterial activity were detected against anaerobic bacteria and aerobic bacteria. Results: No 1 - anaerobic obviously,No 2 on aerobic bacteria, Er yanning 1-2 compatibility has the dual role of anaerobic bacteria and aerobic bacteria resistance, FIC index showed that additive effect on Bacteroides fragilis and Escherichia coli, respectively 83-82%, 54% of Pseudomonas aeruginosa, synergistic effect of 48%. Conclusions: Er Yanning No 1 and No 2 compatibility has dual affect in antibacterial anaerobic bacteria and aerobic bacteria