Bioactive Component and their Role in Inhibition of Bacterial Meningitis

Ayushi Chaudhary* and Himani Badoni

Bacterial meningitis is a severe ailment present in the peritoneum, mainly filled with CSF. The characteristic triad of meningitis indications of migraine, high temperature, and dystonia are caused by inflammation of the meninges and submucosa, as well as pleocytosis present in the CSF. The pathogenesis of BM requires complicated pathways involving pathogen survivability and proliferation in the stream, enhanced susceptibility of the Blood Brain Barrier (BBB), oxidative stress, and an overactive provocative response present in the CNS. The pathophysiology of bacterial meningitis has been better understood because to experimental and genetic association investigations. The present review paper summaries the pathogenesis of invading pathogens and role of different bioactive compounds taken from different plant extracts that might be helpful in curing the diseases. These bioactive compounds might have the inhibitory factor against the emerging disease and this need to be inculcate by performing various methodologies for future investigations.

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