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Anti-Inflammatory and Antimicrobial Activities of Methanolic Extract of Tribulus Terrestris Linn Plant

B. Baburao, G. Rajyalakshmi, A. Venkatesham, G. Kiran, A. Shyam Sunder and B. Ganga Rao

Tribulus terrestris Linn is a herb of the family Zygophyllaceae, whose parts are known to be used as traditional herbal medicine to treat various aliments such as kidney infections. The methanol extract of Tribulus terrestris plant was screened for anti-inflammatory and antimicrobial activity. The methanolic extract showed a significant inhibition on the growth of Gram (+) and Gram (-) bacteria at concentrations of 200 8g/mL and 400 8g/mL, respectively. A dose dependent inhibition of rat paw volume by methanolic extract of T. terrestris in Carrageenan induced inflammation in rats was observed, which is comparable with standard drug, diclofenac sodium.