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Antidiabetic activity of Parmelia perlata in rats

Vijai Lakshmi, Keerti Ameta, Ravi Sonkar, Mohammad Kaleem Ahmad, Santosh Kumar Agarwal, Abbas Ali Mahdi

The present studywas to evaluate the antidiabetic activity of the Parmelia perlata in streptozotocin induced diabetic rats. The ethanol extract and its chloroform fraction showed promising results. doses respectively. The ethanol extract showed promising activity 21.5% at 500 mg/kg in STZ-s model. On further fractionation of the ethanol extract into four fractions, the activity was localized only in hexane and chloroformfractions (at 250 mg/kg hexane fraction showed 20.33% and chloroform fraction showed 30.2%). Themost active fractionwas chloroformfraction. Furtherwork on this fraction is in progress and the active molecules from this fraction will be reported later.