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Antidiabetic activity of bark extract of Pithecellobium dulce benth in alloxan-induced diabetic rats

A.Raghu Praveen, K.Hari Prasath, P.Venkatesh, B.Venkata Kalyan, I.Sudheer Babu

The present study was undertaken to evaluate the Antidiabetic activity of bark of Pithecellobium ducle Benth. Hydro alcoholic bark extract of Pithecellobium ducle Benth was subjected to qualitative phytochemical analysis which showed the presence of sterols, alkaloids, glycosides, saponins, tannins, carbohydrates, proteins, flavonoids and phenolic compounds. The extract at dose levels of 200mg/kg.b.wt and 400mg/kg.b.wt were screened for antidiabetic activity in alloxan induced rats. The extract at dose level of 400mg/kg.b.wt showed a significant antidiabetic activity (p<0.05) when compared to standard Glibenclamide and also showed significant decrease in cholesterol and triglyceride levels (p<0.05) when compared to control diabetic rats.