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Anthelmintic Property of Zizyphus Oenoplia

Manoj Singh and J. P. Singh

Only fewer medicinal plant shows anthelmintic property in which Zizyphus oenoplia is one of them. The worm disease cause by pheretima pootums is common in eastern U.P. (India). The aim of present study was to investigate the preliminary phytochemical constituent and anthelmintic activity of Zizyphus oenoplia against earthworm (Pheretima postuma). The concentrations (20, 50 & 100 mg/mL) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worms. The total alcoholic extract and its ethanolic and aqueous fraction exhibited anthelmintic activity at highest concentration of 100 mg/mL. Piperazine citrate in same concentration as that of extract was included as standard reference and normal saline water as control. So it could be confirmed that the total alcoholic extract, ethanol fraction and aqueous fraction of root of Zizyphus oenoplia showed significant anthelmintic properties comparable with standard durg, which is effective against parasitic infection of humans.