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Acute Diuretic Activity Of Withania Somnifera (L.) Dunal Leaves in Normal Rats

Avijeet Jain, Lokesh Deb, Sunita Panchawat, Anurekha Jain, V.B.Gupta

This work was undertaken to investigate diuretic activity of Withania Somnifera. Aqueous extract of leaves (100 mg/kg) was taken for screening of diuretic activity in albino rats after defatting and detoxification with petroleum ether and chloroform respectively. Frusemide was used as standard drug. The aqueous extract has shown significant diuretic activity which may be due to presence of polar compounds in Withania Somnifera.